SCIENTIST, TARGET PROTEIN SCIENCES, BIOLOGICS DISCOVERY

Johnson & Johnson is recruiting for a Scientist, Target Protein Sciences, Biologics Discovery to join our team in Spring House, PA.
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The Target Protein Sciences group, within Biologics Discovery, at Johnson and Johnson Innovative Medicine is looking for a hardworking and experienced scientist to drive membrane protein production efforts.
We are a multifaceted Biologics Discovery organization, with a diverse and focused team of scientists committed to bringing the next generation of biotherapeutic molecules to patients.
We are looking for a highly motivated Scientist to drive internal and external efforts for membrane protein expression and optimization, purification, and production and characterization for supporting a robust biotherapeutics pipeline.
The ideal candidate will have experience in molecular biology, protein biochemistry and cell biology.
Applicants having a demonstrated track record with membrane protein production and purification will be most desirable.
The successful candidate should be able to work collaboratively in a fast-paced, multi-team environment while supporting various programs across several different therapeutic areas.
Additional knowledge in biologics discovery, immunology, oncology, or other human diseases would be a plus.
Prior industry experience is advantageous but not required.
Key Responsibilities.
Support membrane protein expression and optimization, and purification.
Conduct protein production, purification and characterization.
Characterization and quality check of membrane proteins to support biotherapeutics development.
Utilize expertise in molecular biology, protein biochemistry, and cell biology.
Collaborate effectively in a multi-team environment.
Support various programs across different therapeutic areas.
Contribute to both internal and external efforts in membrane protein production.
production.
Qualifications Education.
Minimum of BS Degree with a minimum of 4 years of academic/industry experience or MS Degree with a minimum of 2 years is required.
Experience and Skills.
Required.
Knowledge of protein expression construct design and optimization, and expression platforms Experience with protein purification and understanding of analytical characterization to determine quality, conformation, purity and stability Experience with mammalian and/or insect cell culture Excellent communication skills to collaborate with internal and external partners Preferred.
Experience with membrane protein expression and optimization, purification, and characterization of proteins Proficient in protein purification optimization, detergent screening, and reconstitutions into lipid nanodiscs Experience in independently operating AKTA FPLC and analytical HPLC instruments Experience in generating DNA/RNA constructs and or other tools as antigen for supporting antibody discovery Knowledge and experience with CROs for protein production Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
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