SCIENTIST

Site Name: Italy - Siena Posted Date: Nov 19 2024 Are you energized by a challenging role in analytics and automation, where scientific demand is driving team growth? If so, this Scientist role would be a great opportunity to consider. As a Scientist specialized in analytical development, you will join a team of experts focusing on development of in-process analytics to support Drug Substance process development for vaccine from Phase I up to commercial launch. You will closely collaborate with an Early Development team for the initial development phases of the new vaccine candidates. You will collaborate with the process development team to develop in-process strategy and implement fit for purpose analytical tools in the scope of upstream and downstream processes development. In this role: You will be expected to lead, autonomously, development of in-process analytics (immuno and chemical-physical assays), explore and introduce new technologies and analytical applications to characterize new antigen vaccine candidates quality attributes in complex matrixes, both in USP and DSP process intermediates. You will be expected to perform timeline planning estimations, design development strategies, plan experimental protocols and execute them in coordination with the other team members of the Development Unit, having a strong presence in the lab to ensure best practices, compliance with documentation practices and EHS standards. You will be expected to follow the Quality by Design approach to process development, leading multidisciplinary Technical Risk Assessments and ensuring to meet all documentation deliverables required at each of the project stage gates. You will be expected to support the In-Process Analytical Head in bringing the team to the next level in terms of technical knowledge and best practices, proactively promoting initiatives. Why you? Basic Qualifications: Scientific degree in biotechnology, bioengineering, biochemistry, chemistry or equivalent Strong experience in: analytical development (especially immuno assay development for drug substance process characterization), development of automated assay (using liquid handler), development of biophysical and immuno tools to characterize proteins, polysaccharides and glyco-conjugates Knowledge of legacy, current-gen and next-gen vaccine manufacturing technologies Sound scientific methodology, critical thinking and problem-solving skills and ability to work in a dynamic multidisciplinary environment Strong organizational skills and communication skills English proficiency (written and spoken) Preferred Qualifications: PhD in biotechnology, bioengineering, biochemistry, chemistry or equivalent Previous experience in analytical development for vaccines antigen development. Understanding of clinical and commercial manufacturing processes and manufacturing constraints Knowledge of Upstream/Downstream Drug Substance Development and/or Manufacturing in biopharma/biotech industry Deep understanding of Quality by Design principles and deliverables What We Offer: Permanent contract in a very Inclusive environment Performance Reward Flexible Benefits Company Healthcare Plan Integrative pension fund Employee Assistance Programme Prevention services and vaccination clinic Tax assistance Local nursery agreement On Site Gym On Site canteens and coffee corners Free company bikes and shuttle Closing Date for Applications – November 26th, 2024 Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together. #J-18808-Ljbffr