RESEARCHER IN CANCER AND RADIATION BIOLOGY

Researcher in cancer and radiation biology The Department of Molecular Biosciences, Wenner-Gren Institute (MBW) conducts experimental basic research in molecular cell biology, integrative biology and infection and immune biology. The research environment is characterized by a modern and advanced methodology and has a strong international profile. MBW is one of the larger departments of the Faculty of Science at Stockholm University with more than 30 research groups and about 200 employees, of whom 65 are doctoral students. Read more about MBW at . Project description The position will be associated with the EU-funded project MIRAMARE (mechanisms of the inversed relationship between menarche age and radiation-induced breast and endometrial cancers) which is supported by the European Partnership for Radiation Protection Research PIANOFORTE. The project aims at elucidating the mechanisms responsible for the inversed relationship between menarche age and the risk of radiation-induced breast and endometrial cancer. A factor responsible for early menarche age is obesity. It is possible that the inversed correlation between menarche age and cancer results from the interaction of obesity-related factors, sex hormones and radiation. The aim of MIRAMARE is to test this hypothesis by using in vitro cell model systems. The project is a collaboration between partners from France, Italy, Poland and the UK. Main responsibilities The position involves application of cell culture and molecular biology techniques to analyse DNA damage and repair induced by radiation in combination with sex and obesity hormones. Analyses will include fluorescent microscopy of painted chromosomes. All exposure facilities are installed at Stockholm University. Involvement in work funded by other relevant projects may also constitute a part of the work. The selected person will also participate in running a course in radiation biology and cellular toxicology. Qualification requirements Researchers are appointed primarily for purposes of research and must hold a Swedish doctoral degree or an equivalent degree from another country in the field of radiation biology, cell biology, molecular biology or similar areas. Experience from work with normal or cancer breast cell lines is highly advantageous, as well as previous work in the field of radiation biology and cancer biology. Experience with techniques to measure DNA damage and repair (gammaH2AX focus assay, comet assay, chromosomal aberration and micronucleus test) as well as cell death assays (apoptosis, clonogenic cell survival) is regarded as an asset. Additional merits include the use of methods such as real time qPCR and Western blotting. Assessment criteria In the appointment process, attention will be given to research skills and work experience as specified in the qualification requirements. Terms of employment This is a full-time, indefinite-term position with a six-month trial period. Start date 2025-02-01 or as per agreement. Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all. Contact Further information about the position can be obtained from Professor Andrzej Wojcik, telephone: +46 8 16 12 17, ..., or the Department Head, Professor Neus Visa, telephone: +46 8 16 41 11, .... Application Apply for the position at Stockholm University's recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. Please include the following information with your application: Your contact details and personal data and, in addition, please include the following documents: CV – degrees and other completed courses, work experience and a list of publications Research proposal (no more than 3 pages) describing: – why you are interested in the field/project described in the advertisement – why and how you wish to complete the project – what makes you suitable for the project in question Copy of PhD diploma Letters of recommendation (no more than 3 files) Publications in support of your application (no more than 3 files). Stockholm University contributes to the development of sustainable democratic society through knowledge, enlightenment and the pursuit of truth. URL to this page: #J-18808-Ljbffr