POSTDOCTORAL FELLOW - CANCER EPIGENETICS

Postdoctoral Fellow - Cancer Epigenetics IEO - European Institute of Oncology Milan, Italy We are looking for an enthusiastic postdoctoral fellow with strong expertise in molecular and cellular biology to lead a project aimed at identifying epigenetic determinants of acquired resistance to therapy in cancer.
The project is part of a EU-funded collaborative study that involves five high-profile partners across Europe.
The study will employ SmartCodes, next-generation molecular barcodes developed by our collaborator Greg Hannon in Cambridge UK, which allow prospective isolation and characterization of therapy-resistant cells from treatment naïve tumors.
Depending on candidate’s interests, other projects related to the broader research of the lab may also be considered.
Key experience and competencies.
Essential PhD in molecular and/or cellular biology, biochemistry, or related; Strong expertise in molecular biology (advanced molecular cloning and NGS-based approaches), cell culture(transfection, transduction, clone isolation, medium- or high-throughput cell culturing), basic biochemistry and quantitative microscopy; Good knowledge and expertise in chromatin biology; Track record of writing papers as evidenced by publications or submitted manuscripts in peer-reviewed journals, with a least one first-author publication; Excellent spoken and written English.
Desirable Experience with CRISPR technology, including targeted genome editing and NGS-based read-outs; Experience with molecular barcoding/lineage tracing; Experience with animal work (e.
.
transplantation assays and xenograft models).